The introduction of stratified medicine is dependent on the development of new diagnostic techniques which can be used in the clinic. This relies on access to “real-life” samples to validate tests before they can be adopted in routine clinical practice, appropriately trained staff, and a clear route for translating research findings into diagnostic tests that can benefit patients.
However a MRC review led by Professor Sir Robert Lechler (Kings College, London) identified three main challenges hindering stratification and effective diagnostics:
- Proximity: A separation has developed between academic, pathology services and industrial sectors, limiting collaboration and the delivery of effective diagnostic tests.
- Path: There is a lack of a defined pathway for the development of diagnostics, linking discovery science, and clinical application and providing appropriate coverage and support.
- People: The skills base in the UK must be enhanced, by ensuring the provision of appropriate training and support in Molecular Pathology techniques, and increasing the capacity in data analysis and health economics.
The full review can be found at https://www.mrc.ac.uk/documents/pdf/mrc-molecular-pathology-review/